2018
Gil M, Rodríguez-Miguel A, Montoya-Catalá H, González-González R, Álvarez-Gutiérrez A, Rodríguez-Martín S, García-Rodríguez LA, de Abajo FJ. Validation study of colorectal cancer diagnosis in the Spanish primary care database, BIFAP. Pharmacoepidemiol Drug Saf. 2018 Dec 12
Raman SR, Man KKC, Bahmanyar S, Berard A, Bilder S, Boukhris T, Bushnell G, Crystal S, Furu K7, KaoYang YH, Karlstad Ø, Kieler H, Kubota K, Lai EC, Martikainen JE, Maura G, Moore N, Montero D, Nakamura H, Neumann A, Pate V, Pottegård A, Pratt NL, Roughead EE, Macias Saint-Gerons D, Stürmer T, Su CC8, Zoega H, Sturkenbroom MCJM, Chan EW, Coghill D, Ip P, Wong ICK. Trends in attention-deficit hyperactivity disorder
medication use: a retrospective observational study using population-based databases. Lancet Psychiatry. 2018 Oct;5(10):824-835
Rodríguez-Martín S, Martín-Merino E, Lerma V, Rodríguez-Miguel A, González O5, González-Herrada C, Ramírez E, Bellón T, de Abajo FJ. Active surveillance of severe cutaneous adverse reactions: A case-population approach using a registry and a health care database. Pharmacoepidemiol Drug Saf. 2018 Jul 27. doi: 10.1002/pds.4622. [Epub ahead of print]
Elisa Martin-Merino, Amaia Calderón-Larrañaga, Samuel Hawley, Beatriz Poblador-Plou, Ana Llorente, Irene Petersen, and Daniel Prieto-Alhambra. The impact of different strategies to handle missing data on both precision and bias in a drug safety study: a multi-database multinational population-based cohort study. Clinical Epidemiology 2018:10
Martín-Merino E, Petersen I, Hawley S, Álvarez-Gutierrez A, Khalid S, Llorente-Garcia A, Delmestri A, Javaid K, Van Staa T, Judge A, Cooper C, Prieto-Alhambra D. Risk of venous thromboembolism amongst users of different anti-osteoporosis drugs: a population-based cohort analysis including over 200,000 participants from Spain and the UK. Osteoporos Int. 2018 Feb;29(2):467-478. doi: 10.1007/s00198-017-4308-5. Epub 2017 Dec 3.
2017
Francisco J. de Abajo, MD; Sara Rodríguez-Martín, PharmD; Antonio Rodríguez-Miguel, PharmD; Miguel J. Gil, MD Risk of Ischemic Stroke Associated With Calcium Supplements With or Without Vitamin D: A Nested Case-Control Study J Am Heart Assoc. 2017 May 18;6(5). pii: e005795. doi: 10.1161/JAHA.117.005795.
Luis Carlos Saiz Fernandez; Javier Garjón Parra; Javier Gorricho Mendívil; Juan Erviti López; Miguel Jesús Gil García; Elisa Martín-Merino; Validation and incidence of Community-Acquired Pneumonia in patients with Type 2 Diabetes in BIFAP database Epidemiol Infect. 2017 Aug 31:1-9. doi: 10.1017/S0950268817001868. [Epub ahead of print]
Martín-Merino E, Huerta-Álvarez C, Prieto-Alhambra D, Álvarez-Gutiérrez A, Montero-Corominas D. Secular trends of use of anti-osteoporotic treatments in Spain: A population-based cohort study including over 1.5million people and more than 12years of follow-up. Bone. 2017 Dec 1;105(Supplement C):292–8.
Gorricho J, Garjón J, Alonso A, Celaya MC, Saiz LC, Erviti J, et al. Use of oral antidiabetic agents and risk of community-acquired pneumonia: a nested case-control study Br J Clin Pharmacol 2017.doi:10.1111/bcp.13288.
Elisa Martín-Merino, Consuelo Huerta-Álvarez, Daniel Prieto-Alhambra, Dolores Montero-Corominas Cessation rate of anti-osteoporosis treatments and risk factors in Spanish primary care settings: a population-based cohort analysis Arch Osteoporos. 2017 Dec;12(1):39. doi: 10.1007/s11657-017-0331-6. Epub 2017 Apr 11.
2016
I. Rivero-Calle, J. Pardo-Seco, P. Aldaz, D. A. Vargas, E. Mascarós, E. Redondo, J. L. Díaz-Maroto, M. Linares-Rufo, M. J. Fierro-Alacio, A. Gil, J. Molina, D. Ocaña, Federico Martinón-Torres and on behalf of NEUMOEXPERTOS group. Incidence and risk factor prevalence of community-acquired pneumonia in adults in primary care in Spain (NEUMO-ES-RISK project). BMC Infect Dis. 2016 Nov 7;16(1):645
Brauer R, Ruigómez A, Downey G, Bate A, Garcia Rodriguez LA, Huerta C, Gil M, de Abajo F, Requena G, Alvarez Y, Slattery J, de Groot M, Souverein P, Hesse U, Rottenkolber M, Schmiedl S, de Vries F, Tepie MF, Schlienger R, Smeeth L, Douglas I, Reynolds R, Klungel O. Prevalence of antibiotic use: A methodological comparison across various European health care data sources Pharmacoepidemiol Drug Saf. 1 de marzo de 2016;25:11-20.
Gema Requena, Consuelo Huerta, Helga Gardarsdottir, John Logie, Rocío González-González,Victoria Abbing-Karahagopian, Montserrat Miret, Cornelia Schneider, Patrick C. Souverein, Dave Webb,Ana Afonso, Nada Boudiaf, Elisa Martin, Belén Oliva, Arturo Alvarez, Mark C. H. De Groot, Andrew Bate,Saga Johansson, Raymond Schlienger, Robert Reynolds, Olaf H. Klungel and Francisco J. de Abajo. Hip/femur fractures associated with the use of benzodiazepines (anxiolytics, hypnotics and related drugs): a methodological approach to assess consistencies across databases from the PROTECT-EU project. Pharmacoepidemiol Drug Saf. 1 de marzo de 2016;25:66-78.
Requena G, Logie J, Martin E, Boudiaf N, González González R, Huerta C, Alvarez A, Webb D, Bate A, García Rodríguez LA, Reynolds R, Schlienger R, Gardarsdottir H, de Groot M, Klungel OH, de Abajo F, Douglas IJ. Do case-only designs yield consistent results across design and different databases? A case study of hip fractures and benzodiazepines. Pharmacoepidemiol Drug Saf. 1 de marzo de 2016;25:79-87.
Udo R, Tcherny-Lessenot S, Brauer R, Dolin P, Irvine D, Wang Y, Auclert L, Juhaeri J, Kurz X, Abenhaim L, Grimaldi L, De Bruin ML. The risk of acute liver injury associated with the use of antibiotics-evaluating robustness of results in the pharmacoepidemiological research on outcomes of therapeutics by a European consortium (PROTECT) project. Pharmacoepidemiol Drug Saf. 1 de marzo de 2016;25:47-55.
Uddin, Md Jamal Groenwold, Rolf H. H. de Boer, Anthonius Gardarsdottir, Helga Martin, Elisa Candore, Gianmario Belitser, Svetlana V. Hoes, Arno W. Roes, Kit C. B. Klungel, Olaf H. Instrumental Variables Analysis Using Multiple Databases: an Example of Antidepressant Use and Risk of Hip Fracture. Pharmacoepidemiol Drug Saf. 1 de marzo de 2016;25:122-31.
M. Sanni Ali, Rolf H. H. Groenwold, Svetlana V. Belitser, Patrick C. Souverein, Elisa Martín, Nicolle M. Gatto, Consuelo Huerta, Helga Gardarsdottir, Kit C. B. Roes, Arno W. Hoes, Antonius de Boer and Olaf H. Klungel. Methodological comparison of marginal structural model, time-varying Cox regression and propensity score methods: the example of antidepressant use and the risk of hip fracture. Pharmacoepidemiol Drug Saf. 1 de marzo de 2016;25:114-21.
Huerta C, Abbing-Karahagopian V, Requena G, Oliva B, Alvarez. Exposure to benzodiazepines (anxiolytics, hypnotics and related drugs) in seven European electronic healthcare databases: a cross-national descriptive study from the PROTECT-EU Project. Pharmacoepidemiol Drug Saf. 1 de marzo de 2016;25:56-65.
MC de Hoyos-Alonso, Bonis J, E Tapias-Merino, MV Castell, A Otero. Estimated prevalence of dementia based on analysis of drug databases in the Region of Madrid (Spain). Neurología (English Edition). Volume 31, Issue 1, January–February 2016. doi:10.1016/j.nrleng.2014.08.003.
Ruigómez A, Brauer R, Huerta C, de Abajo F, Bate A, de Groot M, Schlienger R, Reynolds R, Klungel O, García Rodríguez LA Risk of Acute Liver injury associated with use of antibiotics.
Comparative cohort studies using two primary care databases in Europe Pharmacoepidemiology and drug safety 2016; 25(Suppl. 1): 29-38
Laura Baladé Martíneza, Dolores Montero Corominas y Diego Macías Saint-Gerons Uso del tratamiento hormonal sustitutivo en España: tendenciasen el período 2000-2014. Med Clin (Barc). 2016;147(7):287-292
Macías Saint-Gerons D, Huerta Álvarez C, García Poza P, Montero Corominas D, de la Fuente Honrubia C. Trazodone utilization among the elderly in Spain. A population based study. 2016 Dec 21. pii: S1888-9891(16)30098-2. doi: 10.1016/j.rpsm.2016.11.003. [Epub ahead of print]
2015
Fernando León Vázquez,Julio Bonis Sanz,Verónica Bryant Cerezo, Silvia Herrero Hernández,Lucía Jamart Sánchez, Antonio Díaz Holgado. Prevención de osteoporosis en España: uso de fármacos antes y despues de una fractura de cadera. Rev Osteoporos Metab Miner 2015 [Epub ahead of print]
Sáez-Jiméneza R, Bonis J. Estudio descriptivo sobre el uso de antiinflamatorios no esteroideos por vía intramuscular para el tratamiento de la lumbalgia aguda en las consultas de Atención Primaria en España durante 2002-2011. Rev Clin Med Fam. Vol. 8. Núm. 2
V. Abbing-Karahagopian, P.C. Souverein, E. Martin , C. Huerta, F. de Abajo, H.G.M. Leufkens, G. Candore, Y. Alvarez,J. Slattery, M. Miret, G. Requena, M. Gil, R.H.H. Groenwold, R. Reynolds, R.G. Schlienger, M.C.H. de Groot, O.H. Klungel, T.P. van Staa, A.C.G. Egberts, M.L. De Bruin, H. Gardarsdottir. Understanding inconsistency in the results from observational pharmacoepidemiological studies: the case of antidepressant use and risk of hip/femur fractures. Pharmacoepidemiol Drug Saf. 1 de marzo de 2016;25:88-102.
Diego Macías Saint-Gerons, Cesar de la Fuente Honrubia, Fernando de Andres-Trelles, Ferran Catala Lopez. Prevencion primaria de las enfermedades cardiovasculares con estatinas en pacientes con diabetes. Med Clin (Barc). 2015;144(6):282-287.
Patricia García-Poza, PharmD; Francisco J de Abajo, MD, PhD, MPH; Miguel J. Gil, MD, PhD, MPH ; Ana Chacón, MD, PhD, Verónica Bryant, NP; Luis A. García-Rodríguez MD, MSc. Risk of nonfatal ischemic stroke associated with non-steroidal antiinflammatory drugs and acetaminophem: a nested case-control study. J Thromb Haemost. 2015;13(5):708-18.
Rottenkolber M, Voogd E, van Dijk L, Primatesta P, Becker C, Schlienger R, de Groot M, Plana E, Alvarez Y, Durand J, Slattery J, Afonso A, Requena G, Gil M, Huerta C, Alvarez A, de Abajo F, Hesse U, Fischer R, Hasford J, Gerlach R, Tauscher M, Reynolds R, Klungel O, Schmiedl S *equal contribution. Time trends of period prevalence rates of patients with inhaled long-acting beta-2-agonists-containing prescriptions: a European comparative database study. PLoS One. 2015 Feb 23;10(2):e0117628.
Martin E, de Abajo FJ, Gil M. Risk of toxic epidermal necrolysis and Steven-Johnson syndrome associated with benzodiazepines: a population-based cohort study. Eur J Clin Pharmacol. 2015 Jun;71(6):759-66.
De Abajo F, Gil Miguel, García-Poza Patricia, Alvarez Arturo, Bryant Verónica, García-Rodríguez, Luis. Allopurinol use is associated with a decrease in the risk of non-fatal acute myocardial infarction: evidence from a nested case-control study. Heart 2015:101;679-685.
Diego Macías Saint-Gerons, César de la Fuente Honrubia, Diana González Bermejo, Dolores Montero, Miguel J Gil, Antonio Salvador Sanz, Fernando de Andrés-Trelles y Ferrán Catalá-López. Utilización de la terapia intensiva con estatinas en la prevención secundaria de enfermedad vascular en España. Rev Esp Salud Pública 2015;89: 159-171.
María del Canto de Hoyos-Alonso, Julio Bonis, Verónica Bryant, María Victoria Castell Alcalá, Ángel Otero Puime. Calidad del registro del diagnóstico de demencia en atención primaria. La situación en España en el periodo 2002-2011. Aten Primaria. 2015.
Rottenkolber M, Voogd E, van Dijk L, Primatesta P, Becker C, de Groot MC, Plana E, Alvarez Y, Durand J, Slattery J, Afonso A, Requena G, Huerta C, Alvarez A, de Abajo F, Tauscher M, Hasford J, Fischer R, Reynolds R, Schmiedl S. Seasonal changes in prescribing of long-acting beta-2-agonists-containing drugs. Respir Med. 2015 Jul;109(7):828-37.
Sabaté M, Ferrer P, Ballarín E, Rottenkolber M, Amelio J, Schmiedl S, Reynolds R, Klungel O, Ibáñez L; PROTECT Work Package 2. Inpatient drug utilization in Europe: nationwide data sources and a review of publications on a selected group of medicines (PROTECT project). Basic Clin Pharmacol Toxicol. 2015 Mar;116(3):201-11.
2014
RHH Groenwold, MJ Uddin, KCB Roes, A de Boer, E Rivero-Ferrer, E Martin, NM Gatto, OH Klungel. Instrumental variable analysis in randomized trials with non-compliance and observational pharmacoepidemiologic studies. OA Epidemiology 2014 May 09;2(1):9.
MC de Hoyos-Alonso, Bonis J, E Tapias-Merino, MV Castell, A Otero. Estimación de la prevalencia de demencia a partir del análisis de bases de datos sobre uso de fármacos. La situación en la Comunidad de Madrid (España). Neurologia. 2014 Nov 15. pii: S0213-4853(14)00177-7. doi: 10.1016/j.nrl.2014.08.008. [Epub ahead of print].
Ruigómez A, Brauer R, García Rodríguez LA, Huerta C, Requena G, Gil M, Francisco de Abajo, Downey G, Bate A, Feudjo Tepie M, de Groot M, Schlienger R, Reynolds R, Klungel O. Ascertainment of Acute Liver Injury in two European primary care databases. Eur J Clin Pharmacol. 2014 Oct;70(10):1227-35.
Requena G, Abbing-Karahagopian V, Huerta C, De Bruin ML, Alvarez Y, Miret M, Hesse U, Gardarsdottir H, Souverein PC, Slattery J, Schneider C, Rottenkolber M, Schmiedl S, Gil M, De Groot MC, Bate A, Ruigómez A, García Rodríguez LA, Johansson S, de Vries F, Montero D, Schlienger R, Reynolds R, Klungel OH, de Abajo FJ. Incidence rates and trends of hip/femur fractures in five european countries:comparison using e-health records databases. Calcif Tissue Int. 2014 Jun;94(6):580-9.
Abbing-Karahagopian V, Kurz X, Vries Fd, van Staa TP, Alvarez Y, Hesse U, Hasford J, Dijk Lv, de Abajo FJ, Weil JG, Grimaldi-Bensouda L, Egberts AC, Reynolds RF, Klungel OH.. Bridging Differences in Outcomes of Pharmacoepidemiological Studies: Design and First Results of the PROTECT Project. Curr Clin Pharmacol. 2014 May;9(2):130-8.
Mark C. H. de Groot, Markus Schuerch, Frank de Vries, Ulrik Hesse, Belén Oliva, Miguel Gil, Consuelo Huerta, Gema Requena, Francisco de Abajo, Ana S. Afonso, Patrick C. Souverein,Yolanda Alvarez, Jim Slattery, Marietta Rottenkolber, Sven Schmiedl, Liset Van Dijk, Raymond G. Schlienger, Robert Reynolds, and Olaf H. Klungel. Antiepileptic drug use in seven electronic health record databases in Europe: A methodologic comparison. Epilepsia 2014; 55(5):666-673.
V. Abbing-Karahagopian, C. Huerta , P.C. Souverein, F. de Abajo, H. Gardarsdottir, J. Slattery, Y. Alvarez, M. Miret, M. Gil, U. Hesse, G. Requena, F. de Vries, S. Schmiedl, M. Rottenkolber, R. Reynolds, R. Schlienger, M.C.H. de Groot, O.H. Klungel, T.P. van Staa, L. van Dijk, A.C.G. Egberts, H.G.M. Leufkens, M.L. De Bruin. Antidepressant prescribing in five European countries: application of common definitions to assess the prevalence, clinical observations and methodological implications. Eur J Clin Pharmacol. 2014 Jul;70(7):849-57.
De Abajo Francisco, Gil Miguel, García-Poza Patricia, Bryant Verónica, Oliva Belén, Timoner Julia, García-Rodríguez Luis. Risk of acute myocardial infarction associated with use of nonsteroidal antiinflammatory drugs, non-narcotic analgesics and other antirheumatic agents: a nested case-control study. Pharmacoepidemiol Drug Saf. 2014 Apr 1. doi: 10.1002/pds.3617.
2013
Macías Saint-Gerons D, de la Fuente Honrubia C, Montero Corominas D, Gil MJ, de Andrés-Trelles F, Catalá-López F. Standard and intensive lipid-lowering therapy with statins for the primary prevention of vascular diseases: a population-based study. Eur J Clin Pharmacol DOI 10.1007/s00228-013-1586-5.
Bonis J , de Hoyos MC, Llorente A, Gil M, Montero D, de Abajo FJ. Prevalencia de uso de fármacos para el tratamiento de la enfermedad de Alzheimer y su evolución temporal: un estudio descriptivo con la base de datos de atención primaria BIFAP.. Alzheimer. Real Invest Demenc 2013;54:20-27.
Juan Erviti, Álvaro Alonso, Javier Gorricho, Antonio López. Oral bisphosphonates may not decrease hip fracture risk in elderly Spanish women: a nested case-control study. BMJ Open 2013;3:e002084 doi:10.1136/bmjopen-2012-002084.
Juan Erviti, Álvaro Alonso, Belén Oliva, Javier Gorricho, Antonio López, Julia Timoner, Consuelo Huerta, Miguel Gil, Francisco De Abajo. Oral bisphosphonates are associated with increased risk of subtrochanteric and diaphyseal fractures in elderly women: a nested case-control study. Erviti J, Alonso Á, Oliva B, et al. BMJ Open 2013;3:e002091. doi:10.1136/bmjopen-2012-002091.
2012
de Abajo FJ, Gil M, Bryant V, Timoner J, Oliva B, García-Rodriguez LA. Upper gastrointestinal bleeding associated with NSAIDs, other drugs and interactions: an nested case-control study in a new general practice database. Eur J Clin Pharmacol 2012;25:Epub ahead of print].
2011
Gil M, Oliva B, Timoner J, Maciá MA, Bryant V, de Abajo FJ. Risk of meningioma among users of high doses of cyproterone acetate as compared with the general population: evidence from a population-based cohort study.. Br J Clin Pharmacol. 2011;72:965-8.
2010
Chacón García A, Ruigómez A y García Rodríguez LA. Incidencia de neumonía adquirida en la comunidad en la cohorte poblacional de la base de datos en Atención Primaria(BIFAP). Aten Primaria.2010;42:543-551.
2006
Hernández-Díaz S, García Rodríguez LA. Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications. BMC Medicine 2006; 4:22.
2004
de Abajo FJ, García Rodríguez LA. Consumo de ácido acetilsalicílico en pacientes con diabetes mellitus (letter). Med Clin 2004;123:236-9.
2002
Salvador Rosa, J.C. Moreno Pérez, D. Sonego, L.A. García Rodríguez, F.J. de Abajo Iglesias. El Proyecto BIFAP: Base de datos para la Investigación Farmacoepidemiológica en Atención Primaria. Aten Primaria 2002; 30: 655-661.
